This course prepares students to lead adaptive change across healthcare organizations and public health systems, with particular emphasis on regional and rural contexts. Students examine the relationships among leadership, community, organizational culture, and change management in complex, equity-centered, and resource-constrained environments. The course integrates leadership approaches, strengths, values, and asset-based approaches, systems thinking, and strategic change frameworks to strengthen both relational leadership capacity and settings-based effectiveness. Emphasis is placed on addressing structural inequities, navigating workforce challenges, leveraging human resources strategically, and fostering cross-sector collaboration across healthcare and community health settings. Students apply course concepts through a systems-focused project to improve healthcare delivery and population health outcomes. Cross-listed with PH 726.